DTU Chemistry - Pippi

Publications & Presentations

DTU Chemistry


Conformational Stability Study of a Therapeutic Peptide Plectasin Using Molecular Dynamics Simulations in Combination with NMR.

Indrakumar S, Zalar M, Pohl C, Nørgaard A, Streicher W, Harris P, Golovanov AP, Peters GHJ. J Phys Chem B. 2019 May 31.




Novel Non-linear Curve Fitting to Resolve Protein Unfolding Transitions in Intrinsic Fluorescence Differential Scanning Fluorimetry.

Augustijn D, Mahapatra S, Streicher W, Svilenov H, Kulakova A, Pohl C, Rinnan Å. Eur J Pharm Biopharm. 2019 Jun 5.


Ludwig-Maximilans University Munich


Application of interpretable artificial neural networks to early monoclonal antibodies development.

Gentiluomo L, Roessner D, Augustijn D, Svilenov H, Kulakova A, Mahapatra S, Winter G, Streicher W, Rinnan Å, Peters GHJ, Harris P, Frieß W. Eur J Pharm Biopharm. 2019 May 18.


Rapid sample-saving biophysical characterisation and long-term storage stability of liquid interferon alpha2a formulations: Is there a correlation?

Svilenov H, Winter G. Int J Pharm. 2019 May 1.


The ReFOLD assay for protein formulation studies and prediction of protein aggregation during long-term storage.

Svilenov H, Winter G. Eur J Pharm Biopharm. 2019 Apr.


A New Approach to Study the Physical Stability of Monoclonal Antibody Formulations-Dilution From a Denaturant.

Svilenov H, Gentiluomo L, Friess W, Roessner D, Winter G. J Pharm Sci. 2018 Dec.


Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils.

Yordanova Y, Vanderlinden W, Stoll R, Rüdiger D, Tosstorff A, Zaremba W, Winter G, Zahler S, Friess W. Sci Rep. 2018 Jul 26. 


Isothermal chemical denaturation as a complementary tool to overcome limitations of thermal differential scanning fluorimetry in predicting physical stability of protein formulations.

Svilenov H, Markoja U, Winter G. Eur J Pharm Biopharm 2018 Apr.


Astra Zeneca


Interaction of a Macrocycle with an Aggregation-Prone Region of a Monoclonal Antibody.

Martinez Morales M, Zalar M, Sonzini S, Golovanov AP, van der Walle CF, Derrick JP1. Mol Pharm. 2019 May 24. 


Lund University

Total Description of Intrinsic Amphiphile Aggregation: Calorimetric Study and Molecular Probing.

Fernandez-Alvarez R, Medoš Ž, Tošner Z, Zhigunov A, Uchman M, Hervø-Hansen S, Lund M, Bešter-Rogač M, Matějíček P. Langmuir. 2018 Nov 27. 


University of Manchester

Studies of the oligomerisation mechanism of a cystatin-based engineered protein scaffold.

Matja Zalar, Sowmya Indrakumar, Colin W. Levy, Richard B. Tunnicliffe, Günther H. J. Peters, Alexander P. Golovanov A. Sci Rep 2019 Jun 21; 9(1):9067.


Models for Antibody Behavior in Hydrophobic Interaction Chromatography and in Self-Association.

Hebditch M, Roche A, Curtis RA, Warwicker J. J Pharm Sci. 2019.